4.7 Article

An electrochemical approach for detection of DNA methylation and assay of the methyltransferase activity

期刊

CHEMICAL COMMUNICATIONS
卷 47, 期 10, 页码 2844-2846

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05153e

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资金

  1. National Natural Science Foundation of China [20773067, 20833006, 20905036]
  2. Foundation of the Jiangsu Education Committee [09KJA150001, 09KJB150006, 10KJB150009, CX09B_307Z]

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This work develops an electrochemical approach for rapid detection of the genomic DNA methylation level, assay of methyltransferase activity, and evaluation and screening of the inhibitors of methyltransferase. This method may be a help for the discovery of anticancer drugs.

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