A turn-on fluorescent probe for hypochlorous acid: convenient synthesis, good sensing performance, and a new design strategy by the removal of C = N isomerization

A new design strategy for the development of fluorescent turn-on chemodosimeters toward OCl(-) was proposed by the removal, but not the general inhibition, of the C=N isomerization. Accordingly, Flu-1 was prepared, which, as shown in the fluorescent picture, exhibited the off-on response for OCl-, sensitively and selectively.