Solubilization of pristine fullerene by the unfolding mechanism of bovine serum albumin for cytotoxic application

A method for solubilization of pristine fullerene (C60) in water was proposed by directly using bovine serum albumin (BSA) as a solubilizer'' by means of the unfolding mechanism. C(60) aqueous solution with a small distribution size, excellent dispersion stability and high dispersion concentration was obtained without the use of derivatization and organic solvent.