期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 18, 页码 5184-5186出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10167f
关键词
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资金
- World Class University (WCU) [R33-2008-000-10003]
- Ministry of Education, Science and Technology [2009-0093818]
- NIH at Utah [GM-057052]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM057052] Funding Source: NIH RePORTER
Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycle via apoptosis.
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