Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric alpha-chlorination: subsequent epoxide opening with carbon nucleophiles

Merging Jorgensen's and MacMillan's organocatalytic aldehyde chlorinations enables the synthesis of chiral vinylcyclopropanes and (-)-cis-aerangis lactone via terpene-derived 1,2-epoxides.