期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 8, 页码 2267-2269出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04485g
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We present evidence of hydrogen bond formation, not salt formation, as the driving force in the liquefaction of a solid pharmaceutical in the form of a neutral acid-base complex, as exemplified by the liquid formed from a mixture of the local anesthetic lidocaine with fatty acids; these complexes exist at the boundary between simple eutectics and partially ionised ionic liquids.
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