期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 40, 页码 11330-11332出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14107d
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资金
- National Natural Science Foundation of China [21021062, 21027013, 21075064, 90813020]
- National Basic Research Program of China [2007CB925102]
A Zn2+ tetraazamacrocycle complex (2) bearing three naphthalene moieties has been prepared. Complex 2 recognizes, binds and causes damage to DNA, and shows considerable cytotoxicity against human cervical (HeLa), breast (MCF-7) and lung (NCI-H157) cancer cell lines with a different apoptotic pathway from that of cisplatin.
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