期刊
ARTHRITIS RESEARCH
卷 2, 期 5, 页码 379-385出版社
BMC
DOI: 10.1186/ar116
关键词
COX-2 selective inhibitors; cyclo-oxygenase; gastrointestinal side effects; nonsteroidal anti-inflammatory drugs
类别
Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an intensive worldwide search and the introduction of selective COX-2 inhibitors. In this review, recent advances in understanding the mechanism of action of NSAIDs and, in this context, clinical findings on NSAID-induced gastrointestinal side effects are summarized. This knowledge is important for the effective treatment of pain and inflammation, as well as for preventing serious and sometimes lethal gastrointestinal side effects.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据