4.7 Article

CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O-2(center dot-) sensing

期刊

CHEMICAL COMMUNICATIONS
卷 47, 期 30, 页码 8539-8541

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13160e

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资金

  1. National Natural Science Foundation of China [91027035]
  2. Key Program of National Natural Science of China [20933007]
  3. Fundamental Research Funds for the Central Universities [WK1013002]
  4. Shanghai Institutions of Higher Learning

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We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O-2(center dot-)) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

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