期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 17, 页码 4965-4967出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10269a
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资金
- Italian Ministry of Scientific Research
- Associazione Italiana per la Ricerca sul Cancro Funding Source: Custom
We employed primer extension reactions to uncover folding motifs in a nuclease hypersensitive element (NHE) with a complex guanine pattern, located in the human KRAS promoter. We also identified and characterized a new G-rich motif of 21 nt capable of forming a parallel G-quadruplex that is disrupted by protein UP1.
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