4.7 Article

Exo-Cyclopamine-a stable and potent inhibitor of hedgehog-signaling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Multidisciplinary

Cyclopamine and Hedgehog Signaling: Chemistry, Biology, Medical Perspectives

Philipp Heretsch et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Review Biochemistry & Molecular Biology

Modulators of the hedgehog signaling pathway

Philipp Heretsch et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Article Chemistry, Analytical

Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified

Steven Ray Wilson et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)

Article Chemistry, Multidisciplinary

A Biomimetic Approach to C-nor-D-homo-Steroids

Philipp Heretsch et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Chemistry, Multidisciplinary

Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach

Athanassios Giannis et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Editorial Material Medicine, Research & Experimental

Hedgehog signalling in colon cancer and stem cells

Alberto Gulino et al.

EMBO MOLECULAR MEDICINE (2009)

Article Chemistry, Medicinal

Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)

Martin R. Tremblay et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Editorial Material Medicine, General & Internal

The Hedgehog Pathway and Pancreatic Cancer

Manuel Hidalgo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Editorial Material Medicine, General & Internal

Following the Hedgehog to New Cancer Therapies.

Andrzej A. Dlugosz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Chemistry, Organic

Synthesis of All Diastereomers of the Piperidine-Alkaloid Substructure of Cyclopamine

Philipp Heretsch et al.

ORGANIC LETTERS (2009)

Review Pharmacology & Pharmacy

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

Suzie J. Scales et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Review Cell Biology

Hedgehog: functions and mechanisms

Markku Varjosalo et al.

GENES & DEVELOPMENT (2008)

Article Multidisciplinary Sciences

A paracrine requirement for hedgehog signalling in cancer

Robert L. Yauch et al.

NATURE (2008)

Article Cell Biology

Patching the gaps in Hedgehog signalling

Rajat Rohatgi et al.

NATURE CELL BIOLOGY (2007)

Review Biotechnology & Applied Microbiology

Targeting the Hedgehog pathway in cancer

Lee L. Rubin et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Developmental Biology

Stages of normal development in the medaka Oryzias latipes

T Iwamatsu

MECHANISMS OF DEVELOPMENT (2004)

Review Multidisciplinary Sciences

The Hedgehog response network: Sensors, switches, and routers

L Lum et al.

SCIENCE (2004)

Review Oncology

Hedgehog signalling in cancer formation and maintenance

MP di Magliano et al.

NATURE REVIEWS CANCER (2003)

Article Multidisciplinary Sciences

The Hedgehog and Wnt signaling pathways in cancer

J Taipale et al.

NATURE (2001)