期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 32, 页码 9134-9136出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13052h
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资金
- CIHR
- Canadian Digestive Health Foundation (CDHF)
- Canadian Institutes of Health Research [111237]
- Heart and Stroke Foundation of Ontario [NA-6305]
The synthesis of selenium analogues of de-O-sulfonated ponkoranol, a naturally occurring sulfonium-ion glucosidase inhibitor isolated from Salacia reticulata, and their evaluation as glucosidase inhibitors against two recombinant intestinal enzymes maltase glucoamylase (MGAM) and sucrase isomaltase (SI) are described.
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