4.7 Article

Supramolecular hydrogelators of N-terminated dipeptides selectively inhibit cancer cells

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CHEMICAL COMMUNICATIONS
卷 47, 期 47, 页码 12625-12627

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15577f

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  1. NIH [R01CA142746]
  2. NATIONAL CANCER INSTITUTE [R01CA142746] Funding Source: NIH RePORTER

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Consisting of N-terminated diphenylalanine, a new type of supramolecular hydrogelators forms hydrogels within a narrow pH window (pH 5.0 to 6.0) and selectively inhibits growth of HeLa cells, which provides important and useful insights for designing molecular nanofibers as potential nanomedicines.

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