3D vision of human lysozyme adsorbed onto a SBA-15 nanostructured matrix

TEM images of human lysozyme loaded on SBA-15 mesoporous silica were obtained through the immunogold staining (IGS) method. IGS is based on the specific interaction between proteins and colloidal gold-conjugated antibodies. Clear evidence that protein molecules are adsorbed both on the external and on the inner pore surface is presented.