期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 45, 页码 12277-12279出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13518j
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We report a remarkably facile one-pot sonochemical approach to prepare protein microspheres whose shells are covalently decorated with a mannosyl derivative to target Escherichia coli (E. coli), while their cores are encapsulated with tetracycline. Conjugated microspheres induced the agglutination of E. coli and increased the anti-bacterial activity of the encapsulated tetracycline by five fold.
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