期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 1, 页码 173-175出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00980f
关键词
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资金
- National Natural Science Foundation of China [20725308, 90913014, 20721061, TRR61]
- Major Research Plan of China [2006CB932102]
Synthetic riboswitch containing aptamer is constructed in E. coli to regulate the expression of beta-lactamase through small molecule-aptamer interactions, which sharply reduces the antibiotic resistance of the engineered bacteria.
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