期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 18, 页码 5268-5270出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10439j
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资金
- Kraeftens Bekaempelse
- Danish Research Council for Technology and Production [274-07-0172]
Conventional optical nanoparticle pH sensors that are designed for ratiometric measurements in cells have been based on utilizing one sensor fluorophore and one reference fluorophore in each nanoparticle, which results in a relatively narrow dynamic measurement range. This results in substantial challenges when conducting live cell measurements, which often leads to misleading results. In the present work we provide a simple solution to this problem.
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