期刊
CHEMICAL COMMUNICATIONS
卷 46, 期 37, 页码 6953-6955出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01522a
关键词
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资金
- Spanish Ministry of Science and Innovation (MICINN) [AYA2009-13920-C02-02]
- Generalitat de Catalunya
- University of Bologna
- MICINN
- ICREA Funding Source: Custom
The synthesis of Spiro compounds via a Michael-Michael-aldol reaction is reported. The reaction affords spirooxindole derivatives in good yields and in almost diastereo- and enantiopure form. Moreover, the reaction works with several heterocycles such as oxindoles, benzofuranones, pyrazolones or azlactones rendering the final Spiro compounds in good yields and excellent stereoselectivities.
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