相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Severe Acute Respiratory Syndrome Coronaviruses with Mutations in the E Protein Are Attenuated and Promising Vaccine Candidates
Jose A. Regla-Nava et al.
JOURNAL OF VIROLOGY (2015)
Structure based computational assessment of channel properties of assembled ORF-8a from SARS-CoV
Hao-Jen Hsu et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2015)
The ORF4a protein of human coronavirus 229E functions as a viroporin that regulates viral production
Ronghua Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
'Too little, too late?' Will inhibitors of the hepatitis C virus p7 ion channel ever be used in the clinic?
Stephen Griffin
FUTURE MEDICINAL CHEMISTRY (2014)
Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus p7 as a Viable Class of Antivirals Targeting Virion Release
Toshana L. Foster et al.
HEPATOLOGY (2014)
Easily Accessible Polycyclic Amines that Inhibit the Wild-Type and Amantadine-Resistant Mutants of the M2 Channel of Influenza A Virus
Matias Rey-Carrizo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant 531N Mutant of the Influenza A Virus M2 Proton Channel
Yibing Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Nuclear Magnetic Resonance Structure Revealed that the Human Polyomavirus JC Virus Agnoprotein Contains an α-Helix Encompassing the Leu/Ile/Phe-Rich Domain
Pascale Coric et al.
JOURNAL OF VIROLOGY (2014)
Inhibition of the Human Respiratory Syncytial Virus Small Hydrophobic Protein and Structural Variations in a Bicelle Environment
Yan Li et al.
JOURNAL OF VIROLOGY (2014)
The Human Metapneumovirus Small Hydrophobic Protein Has Properties Consistent with Those of a Viroporin and Can Modulate Viral Fusogenic Activity
Cyril Masante et al.
JOURNAL OF VIROLOGY (2014)
Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4
Narayan P. Sastri et al.
JOURNAL OF VIROLOGY (2014)
The Intraviral Protein Interaction Network of Hepatitis C Virus
Nicole Hagen et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Kaempferol Derivatives as Antiviral Drugs against the 3a Channel Protein of Coronavirus
Silvia Schwarz et al.
PLANTA MEDICA (2014)
Two Different Conformations in Hepatitis C Virus p7 Protein Account for Proton Transport and Dye Release
Siok Wan Gan et al.
PLOS ONE (2014)
Bacteria-Based Analysis of HIV-1 Vpu Channel Activity
Robert Taube et al.
PLOS ONE (2014)
The stability of secreted, acid-labile H77/JFH-1 hepatitis C virus (HCV) particles is altered by patient isolate genotype 1a p7 sequences
Elizabeth Atkins et al.
VIROLOGY (2014)
Capsid Protein VP4 of Human Rhinovirus Induces Membrane Permeability by the Formation of a Size-Selective Multimeric Pore
Anusha Panjwani et al.
PLOS PATHOGENS (2014)
Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission
L. W. Meredith et al.
ANTIVIRAL RESEARCH (2013)
Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance
Gabriel A. Cook et al.
BIOCHEMISTRY (2013)
Viroporin activity and membrane topology of classic swine fever virus p7 protein
Hui-Chen Guo et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
The Viroporin Activity of the Minor Structural Proteins VP2 and VP3 Is Required for SV40 Propagation
Kristina M. Giorda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Mutations in hepatitis C virus p7 reduce both the egress and infectivity of assembled particles via impaired proton channel function
Matthew J. Bentham et al.
JOURNAL OF GENERAL VIROLOGY (2013)
Discovery of Novel Dual Inhibitors of the Wild-Type and the Most Prevalent Drug-Resistant Mutant, S31N, of the M2 Proton Channel from Influenza A Virus
Jizhou Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
3-Azatetracyclo[5.2.1.15'8.01,5]undecane Derivatives: From Wild-Type Inhibitors of the M2 Ion Channel of Influenza A Virus to Derivatives with Potent Activity against the V27A Mutant
Matias Rey-Carrizo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Drug-Induced Conformational and Dynamical Changes of the S31N Mutant of the Influenza M2 Proton Channel Investigated by Solid-State NMR
Jonathan K. Williams et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Subcellular Localization and Function of an Epitope-Tagged p7 Viroporin in Hepatitis C Virus-Producing Cells
Gabrielle Vieyres et al.
JOURNAL OF VIROLOGY (2013)
Hepatitis C Virus Induces Interleukin-1β (IL-1β)/IL-18 in Circulatory and Resident Liver Macrophages
Shubham Shrivastava et al.
JOURNAL OF VIROLOGY (2013)
Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-Operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity
Joseph M. Hyser et al.
JOURNAL OF VIROLOGY (2013)
Functional Characterization of the Alphavirus TF Protein
Jonathan E. Snyder et al.
JOURNAL OF VIROLOGY (2013)
Unusual architecture of the p7 channel from hepatitis C virus
Bo OuYang et al.
NATURE (2013)
Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay
Aruna D. Balgi et al.
PLOS ONE (2013)
Ultrastructural analysis of hepatitis C virus particles
Maria Teresa Catanese et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
Jun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation
Kathy Triantafilou et al.
THORAX (2013)
Essential roles of Leu/Ile/Phe-rich domain of JC virus agnoprotein in dimer/oligomer formation, protein stability and splicing of viral transcripts
A. Sami Saribas et al.
VIROLOGY (2013)
The p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2
Jude Juventus Aweya et al.
VIRUS RESEARCH (2013)
Evidence suggesting that HCV p7 protects E2 glycoprotein from premature degradation during virus production
Ali M. Atoom et al.
VIRUS RESEARCH (2013)
Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment
Juliane Gentzsch et al.
PLOS PATHOGENS (2013)
A new pentameric structure of rotavirus NSP4 revealed by molecular replacement
Anita R. Chacko et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2012)
Severe diffraction anisotropy, rotational pseudosymmetry and twinning complicate the refinement of a pentameric coiled-coil structure of NSP4 of rotavirus
Anita R. Chacko et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2012)
The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers
Sook-San Wong et al.
FEBS LETTERS (2012)
HIV-1 Vpu Protein Antagonizes Innate Restriction Factor BST-2 via Lipid-embedded Helix-Helix Interactions
Mark Skasko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Small Hydrophobic Protein of the Human Respiratory Syncytial Virus Forms Pentameric Ion Channels
Siok-Wan Gan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors
Laura F. Wetherill et al.
JOURNAL OF VIROLOGY (2012)
Quantitative Measurement of Human Papillomavirus Type 16 E5 Oncoprotein Levels in Epithelial Cell Lines by Mass Spectrometry
Ziad Sahab et al.
JOURNAL OF VIROLOGY (2012)
Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine
Douglas P. Gladue et al.
JOURNAL OF VIROLOGY (2012)
Genetic Divergence of Rotavirus Nonstructural Protein 4 Results in Distinct Serogroup-Specific Viroporin Activity and Intracellular Punctate Structure Morphologies
Joseph M. Hyser et al.
JOURNAL OF VIROLOGY (2012)
Viroporins: structure and biological functions
Jose Luis Nieva et al.
NATURE REVIEWS MICROBIOLOGY (2012)
Structural basis for proton conduction and inhibition by the influenza M2 protein
Mei Hong et al.
PROTEIN SCIENCE (2012)
Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection
Hui Li et al.
VIROLOGY (2012)
Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
Carmina Verdia-Baguena et al.
VIROLOGY (2012)
M2 protein from Influenza A: from multiple structures to biophysical and functional insights
Timothy A. Cross et al.
CURRENT OPINION IN VIROLOGY (2012)
The p7 Protein of Hepatitis C Virus Forms Structurally Plastic, Minimalist Ion Channels
Danielle E. Chandler et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
A Single Polar Residue and Distinct Membrane Topologies Impact the Function of the Infectious Bronchitis Coronavirus E Protein
Travis R. Ruch et al.
PLOS PATHOGENS (2012)
Encephalomyocarditis Virus Viroporin 2B Activates NLRP3 Inflammasome
Minako Ito et al.
PLOS PATHOGENS (2012)
Analysis of Functional Differences between Hepatitis C Virus NS5A of Genotypes 1-7 in Infectious Cell Culture Systems
Troels K. H. Scheel et al.
PLOS PATHOGENS (2012)
Emodin inhibits current through SARS-associated coronavirus 3a protein
Silvia Schwarz et al.
ANTIVIRAL RESEARCH (2011)
Drug sensitivity, drug-resistant mutations, and structures of three conductance domains of viral porins
Mukesh Sharma et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations
Cheng-Chang Chen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy
Gabriel A. Cook et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71
Shiqi Xie et al.
CELL RESEARCH (2011)
Resistance Mutations Define Specific Antiviral Effects for Inhibitors of the Hepatitis C Virus p7 Ion Channel
Toshana L. Foster et al.
HEPATOLOGY (2011)
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein
Philip Tedbury et al.
JOURNAL OF GENERAL VIROLOGY (2011)
Exploring the Size Limit of Templates for Inhibitors of the M2 Ion Channel of Influenza A Virus
Maria D. Duque et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2
Jun Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
Kenneth A. Stapleford et al.
JOURNAL OF VIROLOGY (2011)
Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins
Yinghong Ma et al.
JOURNAL OF VIROLOGY (2011)
Development and Application of Hepatitis C Reporter Viruses with Genotype 1 to 7 Core-Nonstructural Protein 2 (NS2) Expressing Fluorescent Proteins or Luciferase in Modified JFH1 NS5A
Judith M. Gottwein et al.
JOURNAL OF VIROLOGY (2011)
Novel Pentameric Structure of the Diarrhea-Inducing Region of the Rotavirus Enterotoxigenic Protein NSP4
Anita R. Chacko et al.
JOURNAL OF VIROLOGY (2011)
The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein
Thomas Whitfield et al.
MOLECULAR MEMBRANE BIOLOGY (2011)
The HIV-1 Vpu Viroporin Inhibitor BIT225 Does Not Affect Vpu-Mediated Tetherin Antagonism
Bjoern D. Kuhl et al.
PLOS ONE (2011)
Sublingual Immunization with M2-Based Vaccine Induces Broad Protective Immunity against Influenza
Byoung-Shik Shim et al.
PLOS ONE (2011)
Structural Investigation of Rimantadine Inhibition of the AM2-BM2 Chimera Channel of Influenza Viruses
Rafal M. Pielak et al.
STRUCTURE (2011)
Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes
Sook-San Wong et al.
VIROLOGY (2011)
Human polyomavirus JC small regulatory agnoprotein forms highly stable dimers and oligomers: Implications for their roles in agnoprotein function
A. Sami Saribas et al.
VIROLOGY (2011)
Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317
Sebastian Bolduan et al.
VIROLOGY (2011)
Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in Inhibitors of M2 from Influenza A Virus
Jun Wang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2011)
The SV40 Late Protein VP4 Is a Viroporin that Forms Pores to Disrupt Membranes for Viral Release
Smita Raghava et al.
PLOS PATHOGENS (2011)
A Concerted Action of Hepatitis C Virus P7 and Nonstructural Protein 2 Regulates Core Localization at the Endoplasmic Reticulum and Virus Assembly
Bertrand Boson et al.
PLOS PATHOGENS (2011)
NS2 Protein of Hepatitis C Virus Interacts with Structural and Non-Structural Proteins towards Virus Assembly
Costin-Ioan Popescu et al.
PLOS PATHOGENS (2011)
Development and Validation of a High-Throughput Screening Assay for the Hepatitis C Virus p7 Viroporin
Christian Gervais et al.
JOURNAL OF BIOMOLECULAR SCREENING (2011)
Antiviral Efficacy of the Novel Compound BIT225 against HIV-1 Release from Human Macrophages
Gabriela Khoury et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
A novel Hepatitis C virus p7 ion channel inhibitor, BIT225, inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interferon-α-2b and nucleoside analogues
Carolyn A. Luscombe et al.
ANTIVIRAL RESEARCH (2010)
Membrane Potential Depolarization as a Triggering Mechanism for Vpu-Mediated HIV-1 Release
Kate Hsu et al.
BIOPHYSICAL JOURNAL (2010)
NMR studies of p7 protein from hepatitis C virus
Gabriel A. Cook et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2010)
Direct visualization of the small hydrophobic protein of human respiratory syncytial virus reveals the structural basis for membrane permeability
Stephen D. Carter et al.
FEBS LETTERS (2010)
NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus
Roland Montserret et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Proton Transport through the Influenza A M2 Channel: Three-Dimensional Reference Interaction Site Model Study
Saree Phongphanphanee et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Kinetic Analysis of the M2 Proton Conduction of the Influenza Virus
Rafal M. Pielak et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death
Eric C. Freundt et al.
JOURNAL OF VIROLOGY (2010)
Membrane Orientation of the Human Papillomavirus Type 16 E5 Oncoprotein
Ewa Krawczyk et al.
JOURNAL OF VIROLOGY (2010)
The Human Papillomavirus Type 16 E5 Oncoprotein Inhibits Epidermal Growth Factor Trafficking Independently of Endosome Acidification
Frank A. Suprynowicz et al.
JOURNAL OF VIROLOGY (2010)
Influence of pr-M Cleavage on the Heterogeneity of Extracellular Dengue Virus Particles
Jiraphan Junjhon et al.
JOURNAL OF VIROLOGY (2010)
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Sarah D. Cady et al.
NATURE (2010)
Influenza virus activates inflammasomes via its intracellular M2 ion channel
Takeshi Ichinohe et al.
NATURE IMMUNOLOGY (2010)
Coexistence of two adamantane binding sites in the influenza A M2 ion channel
Matthew R. Rosenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Oligomerization state and supramolecular structure of the HIV-1 Vpu protein transmembrane segment in phospholipid bilayers
Jun-Xia Lu et al.
PROTEIN SCIENCE (2010)
Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer
Mukesh Sharma et al.
SCIENCE (2010)
Mechanisms of Proton Conduction and Gating in Influenza M2 Proton Channels from Solid-State NMR
Fanghao Hu et al.
SCIENCE (2010)
Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease
Jason Netland et al.
VIROLOGY (2010)
The human papillomavirus type 16 E5 oncoprotein synergizes with EGF-receptor signaling to enhance cell cycle progression and the down-regulation of p27Kip1
Adolfo Pedroza-Saavedra et al.
VIROLOGY (2010)
Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity
Joseph M. Hyser et al.
MBIO (2010)
Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production
Ann L. Wozniak et al.
PLOS PATHOGENS (2010)
Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
Vlastimil Jirasko et al.
PLOS PATHOGENS (2010)
The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin
Tadaki Suzuki et al.
PLOS PATHOGENS (2010)
Determination of Pore-Lining Residues in the Hepatitis C Virus p7 Protein
Chee Foong Chew et al.
BIOPHYSICAL JOURNAL (2009)
The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function
Chak-Ming Chan et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding
Sarah D. Cady et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Discovery of Spiro-Piperidine Inhibitors and Their Modulation of the Dynamics of the M2 Proton Channel from Influenza A Virus
Jun Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Energetic analysis of the two controversial drug binding sites of the M2 proton channel in influenza A virus
Qi-Shi Du et al.
JOURNAL OF THEORETICAL BIOLOGY (2009)
Reverse genetic analysis of a putative, influenza virus M2 HXXXW-like motif in the p7 protein of hepatitis C virus
Z. Meshkat et al.
JOURNAL OF VIRAL HEPATITIS (2009)
Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-Complementation
Christiane Brohm et al.
JOURNAL OF VIROLOGY (2009)
Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro
Corine StGelais et al.
JOURNAL OF VIROLOGY (2009)
Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses
George Patargias et al.
MOLECULAR MEMBRANE BIOLOGY (2009)
The SARS Coronavirus 3a Protein Causes Endoplasmic Reticulum Stress and Induces Ligand-Independent Downregulation of the Type 1 Interferon Receptor
Rinki Minakshi et al.
PLOS ONE (2009)
Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus
Ekta Khurana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition
Yuki Ohigashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel
Chunlong Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mechanism of drug inhibition and drug resistance of influenza A M2 channel
Rafal M. Pielak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy
Philipp Luik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Functional and structural characterization of 2B viroporin membranolytic domains
Silvia Sanchez-Martinez et al.
BIOCHEMISTRY (2008)
Poliovirus 2b insertion into lipid monolayers and pore formation in vesicles modulated by anionic phospholipids
Aitziber Agirre et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
Genotype-Dependent Sensitivity of Hepatitis C Virus to Inhibitors of the p7 Ion Channel
Steplien Griffin et al.
HEPATOLOGY (2008)
Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly
Vlastimil Jirasko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Identification of the membrane-active regions of hepatitis C virus p7 protein -: Biophysical characterization of the loop region
Ana J. Perez-Berna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Severe acute respiratory syndrome coronavirus 3a protein activates the mitochondrial death pathway through p38 MAP kinase activation
Kartika Padhan et al.
JOURNAL OF GENERAL VIROLOGY (2008)
Recombinant VP4 of human rhinovirus induces permeability in model membranes
Matthew P. Davis et al.
JOURNAL OF VIROLOGY (2008)
The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding
Benjamin J. Chen et al.
JOURNAL OF VIROLOGY (2008)
Differential Modulation of prM Cleavage, Extracellular Particle Distribution, and Virus Infectivity by Conserved Residues at Nonfurin Consensus Positions of the Dengue Virus pr-M Junction
Jiraphan Junjhon et al.
JOURNAL OF VIROLOGY (2008)
Structure and mechanism of the M2 proton channel of influenza A virus
Jason R. Schnell et al.
NATURE (2008)
Structural basis for the function and inhibition of an influenza virus proton channel
Amanda L. Stouffer et al.
NATURE (2008)
The ties that bind a virus to the cell
Robert P. Kruger
CELL (2008)
Structure and ion channel activity of the human respiratory syncytial virus (hRSV) small hydrophobic protein transmembrane domain
Siok Wan Gan et al.
PROTEIN SCIENCE (2008)
Structure of the immature dengue virus at low pH primes proteolytic maturation
I-Mei Yu et al.
SCIENCE (2008)
Phosphorylation of human polyomavirus BK agnoprotein at Ser-11 is mediated by PKC and has an important regulative function
Mona Johannessen et al.
VIROLOGY (2008)
Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
Pablo Gastaminza et al.
JOURNAL OF VIROLOGY (2008)
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
Stuart J. D. Neil et al.
NATURE (2008)
Biophysical characterization of Vpu from HIV-1 suggests a channel-pore dualism
T. Mehnert et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system
Corine StGelais et al.
ANTIVIRAL RESEARCH (2007)
Conformational changes induced by a single amino acid substitution in the trans-membrane domain of Vpu:: Implications for HIV-1 susceptibility to channel blocking drugs
Sang Ho Park et al.
PROTEIN SCIENCE (2007)
Conductance and amantadine binding of a pore formed by a lysine-flanked transmembrane domain of SARS coronavirus envelope protein
Jaume Torres et al.
PROTEIN SCIENCE (2007)
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus
Eike Steinmann et al.
HEPATOLOGY (2007)
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
Christopher T. Jones et al.
JOURNAL OF VIROLOGY (2007)
Function of the respiratory syncytial virus small hydrophobic protein
Sandra Fuentes et al.
JOURNAL OF VIROLOGY (2007)
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions
Eike Steinmann et al.
PLOS PATHOGENS (2007)
Human papillomavirus 16 E5 oncogene contributes to two stages of skin cardnogenesis
John P. Maufort et al.
CANCER RESEARCH (2007)
Towards a mechanism of function of the viral ion channel Vpu from HIV-1
T. Mehnert et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2007)
Backbone structure of the amantadine-blocked trans-membrane domain M2 proton channel from influenza A virus
Jun Hu et al.
BIOPHYSICAL JOURNAL (2007)
Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4
R. Deepa et al.
ARCHIVES OF VIROLOGY (2007)
The Alphavirus 6K protein activates endogenous ionic conductances when expressed in Xenopus oocytes
Anne-Frederique Antoine et al.
JOURNAL OF MEMBRANE BIOLOGY (2007)
Hepatitis C virus p7 protein is localized in the endoplasmic reticulum when it is encoded by a replication-competent genome
G. Haqshenas et al.
JOURNAL OF GENERAL VIROLOGY (2007)
SV40VP2 and VP3 insertion into ER membranes is controlled by the capsid protein VP1: Implications for DNA translocation out of the ER
Robert Daniels et al.
MOLECULAR CELL (2006)
Drug-protein interaction with Vpu from HIV-1: proposing binding sites for amiloride and one of its derivatives
C. G. Kim et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2006)
Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro
Dean Clarke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Three-dimensional structure of the transmembrane domain of Vpu from HIV-1 in aligned phospholipid bicelles
Sang Ho Park et al.
BIOPHYSICAL JOURNAL (2006)
Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication
Lauren Wilson et al.
VIROLOGY (2006)
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release
Wei Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Model of a putative pore:: The pentameric α-helical bundle of SARS coronavirus E protein in lipid bilayers
Jaume Torres et al.
BIOPHYSICAL JOURNAL (2006)
The coxsackievirus 2B protein increases efflux of ions from the endoplasmic reticulum and Golgi, thereby inhibiting protein trafficking through the Golgi
Arjan S. De Jong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian-human inu-nunodeficiency virus (SHIVKU-1bMC33) susceptible to rimantadine
David R. Hout et al.
VIROLOGY (2006)
Histidines, heart of the hydrogen ion channel from influenza A virus: Toward an understanding of conductance and proton selectivity
J Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Full length Vpu from HIV-1: Combining molecular dynamics simulations with NMR spectroscopy
V Lemaitre et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2006)
Amantadine triple therapy for non-responder hepatitis C patients.: Clues for controversies (ANRS HC 03 BITRI)
M Maynard et al.
JOURNAL OF HEPATOLOGY (2006)
Protein-protein interactions: Modeling the hepatitis C virus ion channel p7
G Patargias et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Structure and dynamics of the HIV-1 Vpu transmembrane domain revealed by solid-state NMR with magic-angle spinning
S Sharpe et al.
BIOCHEMISTRY (2006)
Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHlVKu1bMC33)with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques
DR Hout et al.
VIROLOGY (2006)
Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes
S Griffin et al.
JOURNAL OF VIROLOGY (2005)
Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques
DR Hout et al.
VIROLOGY (2005)
Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene
SMG Williams et al.
CANCER RESEARCH (2005)
Viroporin activity of murine hepatitis virus E protein
V Madan et al.
FEBS LETTERS (2005)
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
T Wakita et al.
NATURE MEDICINE (2005)
Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules - Role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation
T Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells
PTW Law et al.
JOURNAL OF GENERAL VIROLOGY (2005)
Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-golgi pH
GL Disbrow et al.
JOURNAL OF VIROLOGY (2005)
The severe acute respiratory syndrome coronavirus 3a is a novel structural protein
S Shen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Dengue virus M protein C-terminal peptide (DVM-C) forms ion channels
A Premkumar et al.
JOURNAL OF MEMBRANE BIOLOGY (2005)
Analysis of the processing and transmembrane topology of the E2p7 protein of hepatitis C virus
BJ Isherwood et al.
JOURNAL OF GENERAL VIROLOGY (2005)
The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein
Yee-Joo Tan
VIROLOGY JOURNAL (2005)
The coxsackievirus 2B protein suppresses apoptotic host cell responses by manipulating intracellular Ca2+ homeostasis
M Campanella et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel
K Hsu et al.
MOLECULAR CELL (2004)
Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation
V Lemaitre et al.
FEBS LETTERS (2004)
Combination therapy with amantadine and interferon in naive patients with chronic hepatitis C: meta-analysis of individual patient data from six clinical trials
A Mangia et al.
JOURNAL OF HEPATOLOGY (2004)
Alterations of pr-M cleavage and virus export in pr-M junction chimeric dengue viruses
P Keelapang et al.
JOURNAL OF VIROLOGY (2004)
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria
SDC Griffin et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride
A Premkumar et al.
FEBS LETTERS (2004)
Evaluation of amantadine in chronic hepatitis C: a meta-analysis
P Deltenre et al.
JOURNAL OF HEPATOLOGY (2004)
Semliki Forest virus produced in the absence of the 6K protein has an altered spike structure as revealed by decreased membrane fusion capacity
GM McInerney et al.
VIROLOGY (2004)
Channel activity of a viral transmembrane peptide in micro-BLMs:: Vpu1-32 from HIV-1
W Römer et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Role of JC virus agnoprotein in DNA repair
A Darbinyan et al.
JOURNAL OF VIROLOGY (2004)
SARS coronavirus E protein forms cation-selective ion channels
L Wilson et al.
VIROLOGY (2004)
Histidine 39 in the dengue virus type 2 M protein has an important role in virus assembly
MJ Pryor et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Mutational analysis of different regions in the coxsackievirus 2B protein - Requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication
AS de Jong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Three-dimensional structure of the channel-forming trans-membrane domain of virus protein u (Vpu) from HIV-1
SH Park et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Dengue virus M protein contains a proapoptotic sequence referred to as ApoptoM
A Catteau et al.
JOURNAL OF GENERAL VIROLOGY (2003)
The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences
A Sakai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives
D Pavlovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Genome delivery and ion channel properties are altered in VP4 mutants of poliovirus
P Danthi et al.
JOURNAL OF VIROLOGY (2003)
Induction of apoptosis by paramyxovirus Simian virus 5 lacking a small hydrophobic gene
YA Lin et al.
JOURNAL OF VIROLOGY (2003)
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine
SDC Griffin et al.
FEBS LETTERS (2003)
Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle
AS de Jong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
W Zhang et al.
NATURE STRUCTURAL BIOLOGY (2003)
Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes
B Saunier et al.
JOURNAL OF VIROLOGY (2003)
JC virus agnoprotein colocalizes with tubulin
S Endo et al.
JOURNAL OF NEUROVIROLOGY (2003)
Alphavirus 6K proteins form ion channels
JV Melton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Viroporin-mediated membrane permeabilization - Pore formation by nonstructural poliovirus 2B protein
A Agirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Homomultimerization of the coxsackievirus 2B protein in living cells visualized by fluorescence resonance energy transfer microscopy
FJM van Kuppeveld et al.
JOURNAL OF VIROLOGY (2002)
Functional interaction between JC virus late regulatory agnoprotein and cellular Y-box binding transcription factor, YB-1
M Safak et al.
JOURNAL OF VIROLOGY (2002)
Multimerization reactions of coxsackievirus proteins 2B, 2C and 2BC: a mammalian two-hybrid analysis
AS de Jong et al.
JOURNAL OF GENERAL VIROLOGY (2002)
Subcellular localization and topology of the p7 polypeptide of hepatitis C virus
S Carrère-Kremer et al.
JOURNAL OF VIROLOGY (2002)
Structure of dengue virus: Implications for flavivirus organization, maturation, and fusion
RJ Kuhn et al.
CELL (2002)
Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu
GD Ewart et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2002)
Structure of the transmembrane region of the M2 protein H+ channel
JF Wang et al.
PROTEIN SCIENCE (2001)
Sindbis virus variant with a deletion in the 6K gene shows defects in glycoprotein processing and trafficking:: Lack of complementation by a wild-type 6K gene in trans
MA Sanz et al.
JOURNAL OF VIROLOGY (2001)
The structure of the HIV-1 Vpu ion channel: modelling and simulation studies
FS Cordes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2001)
Definitive assignment of proton selectivity and attoampere unitary current to the M2 ion channel protein of influenza A virus
TI Lin et al.
JOURNAL OF VIROLOGY (2001)
NSP4 enterotoxin of rotavirus induces paracellular leakage in polarized epithelial cells
F Tafazoli et al.
JOURNAL OF VIROLOGY (2001)
Crystal structure of the oligomerization domain of NSP4 from rotavirus reveals a core metal-binding site
GD Bowman et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Permeation and activation of the M2 ion channel of influenza A virus
JA Mould et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Direct inhibitory effect of rotavirus NSP4(114-135) peptide on the Na+-D-glucose symporter of rabbit intestinal brush border membrane
N Halaihel et al.
JOURNAL OF VIROLOGY (2000)
Binding of human papillomavirus 16 E5 to the 16 kDa subunit c (proteolipid) of the vacuolar H+-ATPase can be dissociated from the E5-mediated epidermal growth factor receptor overactivation
MI Rodríguez et al.
ONCOGENE (2000)
Membrane-destabilizing activity of rotavirus NSP4 is mediated by a membrane-proximal amphipathic domain
EP Browne et al.
JOURNAL OF GENERAL VIROLOGY (2000)
Modulation of the epidermal growth factor receptor by the human papillomavirus type 16 E5 protein in raft cultures of human keratinocytes
P Tomakidi et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2000)
Probing the structure of rotavirus NSP4: a short sequence at the extreme C terminus mediates binding to the inner capsid particle
JA O'Brien et al.
JOURNAL OF VIROLOGY (2000)
Sequence variants and functional analysis of human papillomavirus type 16 E5 gene in clinical specimens
CH Hsieh et al.
ARCHIVES OF VIROLOGY (2000)