期刊
CHEMICAL COMMUNICATIONS
卷 46, 期 35, 页码 6449-6451出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01763a
关键词
-
资金
- Israel science foundation (ISF) [1011/07]
We determined the added enthalpic and entropic contributions of protective osmolytes to the folding of a model peptide into its native beta-hairpin state. In contrast to entropically driven steric crowding, this study shows that sugars and polyols can act as protective osmolytes by primarily diminishing the unfavourable enthalpic contribution to folding.
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