期刊
CHEMICAL COMMUNICATIONS
卷 46, 期 36, 页码 6684-6686出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01041c
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资金
- National Institute of Biomedical Imaging and Bioengineering (NIBIB)
- MOST of China [2009CB939902, 2010CB631301]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [ZIAEB000073] Funding Source: NIH RePORTER
We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.
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