Enantioselective construction of allylic phosphine oxides through substitution of Morita-Baylis-Hillman carbonates with phosphine oxides

The asymmetric organocatalytic allylic substitution reaction of MBH carbonates with phosphine oxides has been developed. This organocatalytic approach constitutes an easy and efficient method for the direct preparation of allylic phosphine oxides in high enantioselectivities.