4.7 Article

Human serum albumin coated iron oxide nanoparticles for efficient cell labeling

期刊

CHEMICAL COMMUNICATIONS
卷 46, 期 3, 页码 433-435

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ROYAL SOC CHEMISTRY
DOI: 10.1039/b917195a

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资金

  1. Intramural Research Programs of the National Institute of Biomedical Imaging and Bioengineering (NIBIB)
  2. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [ZIAEB000073] Funding Source: NIH RePORTER
  3. CLINICAL CENTER [ZIECL090017] Funding Source: NIH RePORTER

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A novel dopamine-plus-HSA (human serum albumin) approach was developed to functionalize iron oxide nanoparticles (IONPs), yielding nanoconjugates that are highly efficient in labeling various types of cell lines, which was demonstrated by in vivo MR imaging on xenograft and focal cerebral ischemia models.

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