期刊
CHEMICAL COMMUNICATIONS
卷 46, 期 43, 页码 8174-8176出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc03148h
关键词
-
资金
- U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences [W-31-109-Eng-38]
- NIH [R01 GM075993, U54 GM087519]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM075993, U54GM087519] Funding Source: NIH RePORTER
Here we report the total synthesis of kaliotoxin by 'one pot' native chemical ligation of three synthetic peptides. A racemic mixture of D- and L-kaliotoxin synthetic protein molecules gave crystals in the centrosymmetric space group P1 that diffracted to atomic-resolution (0.95 angstrom), enabling the X-ray structure of kaliotoxin to be determined by direct methods.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据