期刊
JOURNAL OF NEUROIMAGING
卷 10, 期 1, 页码 13-16出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1111/jon200010113
关键词
brain; magnetic resonance imaging; white matter hyperintensity
资金
- NATIONAL INSTITUTE ON AGING [R01AG009862, P50AG005144, K04AG000553] Funding Source: NIH RePORTER
- NIA NIH HHS [K04AG00553, 5P50AG05144, R01AG09862] Funding Source: Medline
Periventricular white matter hyperintensities on postmortem magnetic resonance imaging (MRI) and myelin-stained frontal and parietal histologic sections were evaluated independently in 12 cases. There was a strong relationship between the extent of white matter hyperintensities on MRI and the extent of gross and microscopic changes seen in the white matter of myelin-stained sections, particularly in the frontal lobe. In this material, the extent of myelin rarefaction correlated with a 0- to 8-point white matter hyperintensity scale rating on MRI in the same brains.
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