4.7 Article

Ceramide-mediated transport of chloride and bicarbonate across phospholipid membranes

期刊

CHEMICAL COMMUNICATIONS
卷 46, 期 22, 页码 3950-3952

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00493f

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资金

  1. NSF [CHE-0822244]
  2. DOE [DE-FG02-98ER14888]
  3. Howard Hughes Medical Institute (HHMI)
  4. Division Of Chemistry [0822244] Funding Source: National Science Foundation

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The sphingolipid, ceramide 1, facilitates transport of Cl- and HCO3- anions across lipid bilayers under conditions where large transmembrane pores are not formed. Ceramide's 1,3-diol unit is essential for both binding and transporting these anions.

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