Copper(I) scorpionate complexes and their application in palladium-mediated [C-11]carbonylation reactions

Solutions of copper(I) tris( pyrazolyl) borate complexes have been used to greatly improve the solubility of [C-11] carbon monoxide, enabling it to be used in low-pressure, 'one-pot' palladium-mediated carbonylation reactions to form C-11-radiolabelled amides and ureas for use in positron emission tomography.