期刊
CHEMICAL COMMUNICATIONS
卷 -, 期 26, 页码 3055-3057出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b806042h
关键词
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资金
- Biotechnology and Biological Sciences Research Council [BB/C51444X/1] Funding Source: Medline
- Cancer Research UK Funding Source: Medline
Herein we report the de novo design and synthesis of a geometrically flexible bis-indole carboxamide and a constrained derivative, as a novel class of small molecule scaffold that exhibits high stabilization potential for DNA G-quadruplex sequences associated with the promoters of c-kit2 and c-myc.
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