期刊
ORGANIC LETTERS
卷 2, 期 1, 页码 23-26出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol991184t
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资金
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM059380] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01GM59380] Funding Source: Medline
[GRAPHICS] The selective formation of an amide bond in the presence of unprotected functional groups is a challenging problem of peptide chemistry. A 2-mercaptobenzyl group tethered at the N-terminus of model peptides was observed to facilitate amide bond formation when a peptide thioester was added under mild aqueous conditions.
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