相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Eph Receptors and Ephrin Signaling Pathways: A Role in Bone Homeostasis
Claire M. Edwards et al.
International Journal of Medical Sciences (2012)
Therapeutic interference with EphrinB2 signalling inhibits oxygen-induced angioproliferative retinopathy
Christoph Ehlken et al.
ACTA OPHTHALMOLOGICA (2011)
Emerging strategies for EphA2 receptor targeting for cancer therapeutics
Manish Tandon et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Rational Design of a Selective Covalent Modifier of G Protein beta gamma Subunits
Axel L. Dessal et al.
MOLECULAR PHARMACOLOGY (2011)
The resurgence of covalent drugs
Juswinder Singh et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation
Carmine Giorgio et al.
PLOS ONE (2011)
Structure-Activity Relationship Analysis of Peptides Targeting the EphA2 Receptor
Sayantan Mitra et al.
BIOCHEMISTRY (2010)
False Positives in the Early Stages of Drug Discovery
R. Sink et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity
Haina Qin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
Jonathan B. Baell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
Jonathan W. Astin et al.
NATURE CELL BIOLOGY (2010)
The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand
Nai-Ying Yang et al.
PIGMENT CELL & MELANOMA RESEARCH (2010)
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
Elena B. Pasquale
NATURE REVIEWS CANCER (2010)
EphA2 as a promoter of melanoma tumorigenicity
Naira V. Margaryan et al.
CANCER BIOLOGY & THERAPY (2009)
Preferential Induction of EphB4 over EphB2 and Its Implication in Colorectal Cancer Progression
S. Ram Kumar et al.
CANCER RESEARCH (2009)
The road less traveled: modulating signal transduction enzymes by inhibiting their protein-protein interactions
Michelle R. Arkin et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport
Alessandro Filosa et al.
NATURE NEUROSCIENCE (2009)
Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport
Maria A. Carmona et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin-Expressing Cells
Claus Jorgensen et al.
SCIENCE (2009)
Functional significance of VEGF-a in human ovarian carcinoma - Role in vasculogenic mimicry
Jun-yan Wang et al.
CANCER BIOLOGY & THERAPY (2008)
Eph-ephrin bidirectional signaling in physiology and disease
Elena B. Pasquale
CELL (2008)
Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor
Haina Qin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
Roberta Noberini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting
Jill Wykosky et al.
MOLECULAR CANCER RESEARCH (2008)
Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition
Jill E. Chrencik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Reaching for high-hanging fruit in drug discovery at protein-protein interfaces
James A. Wells et al.
NATURE (2007)
Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord
Jez Fabes et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Cell-cell signaling via Eph receptors and ephrins
Juha-Pekka Himanen et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Regulation of angiogenesis by Eph-Ephrin interactions
Sanne Kuijper et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2007)
Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells
Feng-Yao Tang et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2007)
Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors
Jesus Vazquez et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
EphA-ephrin-A-mediated β cell communication regulates insulin secretion from pancreatic islets
Irena Konstantinova et al.
CELL (2007)
Expression of Eph receptor tyrosine kinases and their ligands in human granulosa lutein cells and human umbilical vein endothelial cells
Y. Xu et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2006)
The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization
Nai-Ying Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
EphA4 regulates central nervous system vascular formation
Yona Goldshmit et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Inhibition of retinal neovascularization by soluble EphA2 receptor
J Chen et al.
EXPERIMENTAL EYE RESEARCH (2006)
The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth
N Kertesz et al.
BLOOD (2006)
Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides
A Schirmer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway - Implications for vasculogenic mimicry
AR Hess et al.
CANCER BIOLOGY & THERAPY (2006)
Structure and thermodynamic characterization of the EphB4/ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity
JE Chrencik et al.
STRUCTURE (2006)
Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators
LA Arnold et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
EphA2 as a target for ovarian cancer therapy
CN Landen et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2005)
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion
M Nakada et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets
N Prévost et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Soluble forms of EphrinB2 and EphB4 reduce retinal neovascularization in a model of proliferative retinopathy
DO Zamora et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
EPH receptor signalling casts a wide net on cell behaviour
EB Pasquale
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics
RC Ireton et al.
CURRENT CANCER DRUG TARGETS (2005)
EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity
M Koolpe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of Yersinia tyrosine phosphatase by furanyl salicylate compounds
L Tautz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection
VJ Yao et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist
P Dobrzanski et al.
CANCER RESEARCH (2004)
Phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells
M Nakada et al.
CANCER RESEARCH (2004)
Inhibition of tumor growth and angiogenesis by soluble EphB4
G Martiny-Baron et al.
NEOPLASIA (2004)
Effect of the pyrrole polymerization mechanism on the antioxidative activity of nonenzymatic browning reactions
FJ Hidalgo et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)
Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors
N Cheng et al.
NEOPLASIA (2003)
Targeting the EphA4 receptor in the nervous system with biologically active peptides
KK Murai et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
An ephrin mimetic peptide that selectively targets the EphA2 receptor
M Koolpe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo
DM Brantley et al.
ONCOGENE (2002)
Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
H Miao et al.
NATURE CELL BIOLOGY (2000)
Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos
JG Flanagan et al.
APPLICATIONS OF CHIMERIC GENES AND HYBRID PROTEINS PT B (2000)