期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 62, 期 9, 页码 942-946出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.c14-00312
关键词
speradine; oxindole alkaloid; Aspergillus oryzae; marine-derived fungus
资金
- Chinese National Natural Science Fund [21102015, 31201034]
- Ministry of Education in Fujian Province [WKJ-FJ-14]
- Natural Science Foundation of Fujian Province [2012J05138]
- Department of Science and Technology in Fujian Province [2012Y0017]
- Ministry of Sanitation [WKJ-FJ-14]
A rare hexacyclic oxindole alkaloid, speradine F (1), together with two novel tetracyclic oxindole alkaloids, speradines G (2) and H (3), were isolated from the marine-derived fungus Aspergillus oryzae. Their structures were determined by spectroscopic methods and X-ray diffraction analysis. This study is the first report on cyclopiazonic acid (CPA)-type alkaloids with a hexacyclic skeleton.
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