期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 60, 期 12, 页码 1599-1601出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.c12-00785
关键词
marine sponge; order Verongida; bromotyrosine alkaloid; tyrokeradine
资金
- Akiyama Life Sience Foundation
- Suhara Memorial Foundation
- Ministry of Education, Culture, Sports, Science and Technology of Japan
Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.
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