Tricalysionoside A, a Megastigmane Gentiobioside, Sulfatricalysines A-F, and Tricalysiosides X-Z, ent-Kaurane Glucosides, from the Leaves of Tricalysia dubia

Further isolation work on the water-soluble fraction of a MeOH extract of Tricalysia dubia afforded one new megastigmane gentiobioside, named tricalysionoside A (1), and three sulfates, named sulfatricalysines A-C (2-4) Extensive isolation work on the 1-BuOH-soluble fraction of a MeOH extract of T dubia yielded sulfatricalysines D-F (5-7) and three new ent-kaurane glucosides, named tricalysiosides X-Z (8-10) The structures of the new compounds were elucidated by analyses of one- and two-dimensional NMR spectroscopic data The absolute stereochemistry of tricalysionoside A (1) was established by modified Mosher's method