期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 59, 期 4, 页码 515-517出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.59.515
关键词
penicitrinol; citrinin derivative; cytotoxicity; Penicillium citrinum
资金
- Natural Science Foundation of Fujian Province [2009J05075]
- Scientific Research Foundation in Fuzhou University [2009-XY-16, 022229]
- Scientific Key Research Project of Fujian Province [2010N0015]
- Scientific Major Research Project of Fujian Province [2010NZ0001-1]
Three new citrinin derivatives, penicitrinols C, D, and E (1-3), along with two known compounds, citrinin (4) and decarboxydihydrocitrinone (5), were isolated from Penicillium citrinum. Their structures were determined by spectroscopic methods and X-ray diffraction analysis. Compounds 1 and 3 demonstrated weak cytotoxicity against the HL-60 cell line.
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