期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 56, 期 6, 页码 745-748出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.745
关键词
lutcolin; electroanalysis; pharmaceutical analysis; flavonoid; tablets
Luteolin is a flavonoid reported to occur widely in many medicinal plants. The electrochemical behavior of luteolin was studied in phosphate buffer solution (PBS) of pH 4.0 at a glassy carbon electrode (GCE) by cyclic voltammetry (CV) and differential pulse voltammetric method (DPV). The results indicated the well-defined redox peak of luteolin which was involving two electrons and two protons was observed and the electrode process is adsorption-controlled. The charge transfer coefficient (alpha) was calculated as 0.66. The relationship between oxidation peak current and concentration of luteolin are linear in the range of 1.0x10(-8)-1.0x10(-6)M by DPV method. The detection limit had been estimated as 5.0x10(-9)M. The facile and rapid method has been successfully applied to the detection of luteolin in tablets.
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