Stereoselective conjugate additions of alcohols to a chiral (E)-nitroalkene derived from (R)-2,3-isopropylidene glyceraldehyde

Addition of functionalized alcohols to a chiral (E)-nitroalkene proceeded with modest to high diastereoselectivities depending on the presence of metal catalysts in low temperature. The results indicated that anti-selectivities were preferred in all cases.