期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 176, 期 -, 页码 12-19出版社
ROYAL COLLEGE OF PSYCHIATRISTS
DOI: 10.1192/bjp.176.1.12
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Background Medicine is rapidly becoming molecular medicine. and little escapes the grasp of modern genetics. Most disorders associated with learning disability have at least a genetic component influencing their expression; in many disorders, disturbances of genetic mechanisms play a pivotal role. Aims Dynamic mutations, imprinting mechanisms and gene-dosage effects are explained with reference to genetic disorders that lead to learning disability. Method A review of recent important studies in the genetics of learning disability Results A host of new genetic connections to conditions associated with learning disability have been made. Conclusions A basic understanding of these genetic connections is important for all learning disability psychiatrists if they are to follow the rapid changes - already beginning to influence our practice - that hold immense promise for the future.
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