期刊
BEHAVIOURAL BRAIN RESEARCH
卷 114, 期 1-2, 页码 11-15出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0166-4328(00)00186-8
关键词
vision; acuity; mouse; plasticity; water maze; spatial learning
The effect of richness of the environment on behavioral function was investigated in C57B6 mice. Animals were raised in either enriched (group-housed in large clear plexiglas cages with stimulating objects) or restricted (group housed in opaque white plastic cages with no stimulating objects) environmental conditions and their spatial learning and visual acuity were measured as adults. The performance of enriched and restricted groups were indistinguishable in place and cued versions of the Morris water task; however, the visual acuity of the enriched group, measured in a grating versus gray version of the visual water task, was 18% higher than the restricted group. These data demonstrate that the function of the mouse visual system can be significantly influenced by the nature of early visual input. They also indicate that the effects of environmental enrichment are manifested differently in behavioral measures of spatial learning and visual acuity. (C) 2000 Elsevier Science B.V. All rights reserved.
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