On the wobble GoU and related pairs

The wobble GoU pairs have been implicated in several biological processes where RNA molecules play a key role. We review the geometrical and conformational properties of wobble GoU pairs on the basis of available crystal structures of RNAs at high resolution. The similarities with the wobble A(+)oC pairs and UoU pairs are illustrated, while the differences with the recently discovered bifurcated G.U pairs are contrasted.