期刊
CHEMCATCHEM
卷 11, 期 1, 页码 225-243出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cctc.201801063
关键词
Cascade; biocatalyst; biotransformation; linear biocatalytic cascades; multi-step reaction
资金
- Austrian Science Fund [M 2172, M 2271]
- Austrian Science Fund (FWF) [M2271, M2172] Funding Source: Austrian Science Fund (FWF)
Artificial cascade reactions involving biocatalysts have demonstrated a tremendous potential during the recent years. This review just focuses on selected examples of the last year and putting them into context to a previously published suggestion for classification. Subdividing the cascades according to the number of catalysts in the linear sequence, and classifying whether the steps are performed simultaneous or in a sequential fashion as well as whether the reaction sequence is performed invitro or invivo allows to organise the concepts. The last year showed, that combinations of invivo as well as invitro are possible. Incompatible reaction steps may be run in a sequential fashion or by compartmentalisation of the incompatible steps either by using special reactors (membrane), polymersomes or flow techniques.
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