期刊
CRITICAL REVIEWS IN TOXICOLOGY
卷 31, 期 4-5, 页码 517-522出版社
CRC PRESS LLC
DOI: 10.1080/20014091111794
关键词
testosterone; androgen; hormesis; U shaped; biphasic; stimulatory; inhibitory; dose response; receptor mediated
类别
Testosterone was reported to affect a variety of reproductive endpoints. More notable were the effects of dihydrotestosterone on cell proliferation in the prostate cancer cell model LNCaP and Sertoli cell function. Testosterone production was also biphasically affected by prolactin that was administered to adult testicular cells in vitro.
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