期刊
CHEMBIOCHEM
卷 13, 期 10, 页码 1497-1502出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.201200133
关键词
giant vesicles; membranes; origin of life; polyarginine; vesicles
资金
- EU [043359]
- HFSP [RGP0033/2007-C]
- ASI [I/015/07/0]
- PRIN2008 [2008FY7J4]
Current research on the origin of life typically focuses on the self-organisation of molecular components in individual cell-like compartments, thereby bringing about the emergence of self-sustaining minimal cells. This is justified by the fact that single cells are the minimal forms of life. No attempts have been made to investigate the cooperative mechanisms that could derive from the assembly of individual compartments. Here we present a novel experimental approach based on vesicles colonies as a model of primitive cell communities. Experiments show that several advantages could have favoured primitive cell colonies when compared with isolated primitive cells. In fact there are two novel unexpected features typical of vesicle colonies, namely solute capture and vesicle fusion, which can be seen as the basic physicochemical mechanisms at the origin of life.
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