4.3 Article

Efficient procedure for the preparation of amides using polymer-bound reagents

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SYNTHETIC COMMUNICATIONS
卷 31, 期 7, 页码 1001-1005

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MARCEL DEKKER INC
DOI: 10.1081/SCC-100103528

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An effective method for the conversion of acids into amides is presented. The two-step procedure includes the preparation of acid chloride intermediates using Pol-Ph3P and subsequent treatment of these intermediates with amines and polymer-bound base. The amides were accessible in high yields and purities without further purification.

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