期刊
CEREBROVASCULAR DISEASES
卷 11, 期 2, 页码 128-136出版社
KARGER
DOI: 10.1159/000047624
关键词
computed tomography; ischemic stroke; magnetic resonance imaging; perfusion; single photon emission computed tomography
There have been few direct comparisons between MR perfusion-weighted imaging (PWI) and established perfusion imaging techniques, and none in chronic stroke. We therefore studied 17 chronic hemispheric infarction patients (mean, 90 days) and compared hypoperfusion volumes determined from PWI maps of relative cerebral blood flow (rCBF) and volume (rCBV), and mean transit time (rMTT) with those measured with Tc-99-HMPAO single photon emission computed tomography (SPECT). Comparisons were also made between infarct size (T-2- WI) and clinical scales. Correlations were found between lesion location and volume in all three PWI hemodynamic parameter maps with clinical state and lesions on SPECT and T-2-WI. In 3 patients, rCBF and rCBV lesions extended well beyond the borders of moderate-sized infarctions, We conclude that in chronic stroke, PWI can delineate regions of abnormal perfusion that reflect the degree of functional impairment and structural damage. The finding of peri-infarct hypoperfusion suggests that PWI may have the potential to provide a rapid and noninvasive template against which interventional strategies aimed at promoting functional recovery may be investigated. Copyright (C) 2001 S. Karger AG, Basel.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据