期刊
JOURNAL OF NEURAL TRANSMISSION
卷 108, 期 7, 页码 803-807出版社
SPRINGER-VERLAG WIEN
DOI: 10.1007/s007020170030
关键词
dopamine; lymphocytes; Parkinson's disease
There is increasing interest in the identification of biological markers for the early diagnosis of Parkinson's disease (PD). Previous studies indicate changes of dopamine content, tyrosine hydroxylase immunoreactivity and dopamine receptors in peripheral blood lymphocytes (PBL) in PD. Here we demonstrate a reduction of dopamine transporter immunoreactivity in PBL in the early clinical stages of the disease. These findings contribute to our understanding of the peripheral dopamine system in PD.
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