期刊
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
卷 51, 期 3, 页码 165-168出版社
KARGER
DOI: 10.1159/000052917
关键词
interleukin-8; preterm labour; cervical secretions
The aim of this study was to assess the potential clinical utility of interleukin-8 (IL-8) present in cervical secretions as a marker of preterm labour and delivery, Samples of cervical mucus from 91 pregnant women were assessed for the presence and concentration of IL-8, Two samples were collected (at 18 +/- 2 and 28 +/- 2.5 weeks of gestation) and correlated with cervicovaginal microbiology and cervical length, as measured by transvaginal ultrasound, The IL-8 concentration at 28/40 was significantly higher in women who went on to deliver preterm (p < 0.01), and there was a greater than five-fold increase from 18 to 28 weeks in 6/7 of these women. Copyright (C) 2001 S. Karger AG, Basel.
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