期刊
CEREBRAL CORTEX
卷 24, 期 9, 页码 2377-2387出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cercor/bht091
关键词
cognitive control; executive function; hierarchical; PFC; rule representation
资金
- AFOSR [FA9550-07-1-0454, R03 DA023462, R01 DA026457, F32 NS082069]
- Indiana METACyt Initiative of Indiana University through a major grant from the Lilly Endowment, Inc.
- Intelligence Advanced Research Projects Activity (IARPA) via Department of the Interior (DOI) [D10PC20023]
The functions of the prefrontal cortex (PFC) underlie higher-level cognition. Varying proposals suggest that the PFC is organized along a rostral-caudal gradient of abstraction with more abstract representations/processes associated with more rostral areas. However, the operational definition of abstraction is unclear. Here, we contrasted 2 prominent theories of abstraction-temporal and relational-using fMRI. We further examined whether integrating abstract rules-a function common to each theory-recruited the PFC independently of other abstraction effects. While robust effects of relational abstraction were present in the PFC, temporal abstraction effects were absent. Instead, we found activations specific to the integration of relational rules in areas previously shown to be associated with temporal abstraction. We suggest that previous effects of temporal abstraction were due to confounds with integration demands. We propose an integration framework to understand the functions of the PFC that resolves discrepancies in prior data.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据