期刊
CEREBRAL CORTEX
卷 22, 期 5, 页码 1148-1158出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cercor/bhr189
关键词
brain development; functional areas; functional connectivity; parietal lobe
资金
- National Institutes of Health [NS007205-28, NS062489, NS053425, HD057076, MH091512, NS06114, NS046424]
- Simons Foundation Autism Research Initiative
A key question in developmental neuroscience involves understanding how and when the cerebral cortex is partitioned into distinct functional areas. The present study used functional connectivity MRI mapping and graph theory to identify putative cortical areas and generate a parcellation scheme of left lateral parietal cortex (LLPC) in 7 to 10-year-old children and adults. Results indicated that a majority of putative LLPC areas could be matched across groups (mean distance between matched areas across age: 3.15 mm). Furthermore, the boundaries of children's putative LLPC areas respected the boundaries generated from the adults' parcellation scheme for a majority of children's areas (13/15). Consistent with prior research, matched LLPC areas showed age-related differences in functional connectivity strength with other brain regions. These results suggest that LLPC cortical parcellation and functional connectivity mature along different developmental trajectories, with adult-like boundaries between LLPC areas established in school-age children prior to adult-like functional connectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据