期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 27, 期 3, 页码 113-115出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(01)02049-7
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This article describes a new extracellular domain-AMOP for adhesion-associated domain in MUC4 and other proteins. This domain occurs in putative cell adhesion molecules and in some splice variants of MUC4. MUC4 splice variants are overexpressed in several tumours; in particular, they are highly expressed in pancreatic carcinomas but not in normal pancreas. The presence of AMOP in cell adhesion molecules could be indicative of a role for this domain in adhesion.
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