期刊
NEUROLOGICAL SCIENCES
卷 22, 期 6, 页码 429-435出版社
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s100720200001
关键词
NCAM; PSA-NCAM; myelination; remyelination; multiple sclerosis; steroids; cerebrospinal fluid
The neural cell adhesion molecule (NCAM) is expressed by myelinating precursor cells in neonatal mouse spinal cord and by remyelinating cells after chemically induced demyelination in adult mouse. It shows tempting suggestions about its possible involvement in the reparative mechanisms and the remyelination processes that take place in multiple sclerosis (MS). In fact, its levels progressively increase in the cerebrospinal fluid (CSF) of acute MS patients subjected to steroid treatment, paralleling the progressive clinical improvement after the attack. Such an increase is not found in acute MS patients not treated with steroids nor in non-acute patients subjected to the same steroid treatment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据